User profiles for J. S. Elborn
J Stuart ElbornImperial College and Royal Brompton Hospital, London Verified email at imperial.ac.uk Cited by 44082 |
[HTML][HTML] Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practice
It is often challenging for the clinician interested in cystic fibrosis (CF) to interpret molecular
genetic results, and to integrate them in the diagnostic process. The limitations of genotyping …
genetic results, and to integrate them in the diagnostic process. The limitations of genotyping …
Obesity and the lung: 1· Epidemiology
Obesity is the most common metabolic disease in the world and its prevalence has been
increasing over several decades. The World Health Organization (WHO) predicts that, by 2015, …
increasing over several decades. The World Health Organization (WHO) predicts that, by 2015, …
[HTML][HTML] Treatment of lung infection in patients with cystic fibrosis: current and future strategies
In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation and …
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation and …
[HTML][HTML] A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation
…, K Yen, C Ordoñez, JS Elborn - … England Journal of …, 2011 - Mass Medical Soc
Background Increasing the activity of defective cystic fibrosis transmembrane conductance
regulator (CFTR) protein is a potential treatment for cystic fibrosis. Methods We conducted a …
regulator (CFTR) protein is a potential treatment for cystic fibrosis. Methods We conducted a …
[HTML][HTML] Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR
CE Wainwright, JS Elborn, BW Ramsey… - … England Journal of …, 2015 - Mass Medical Soc
Background Cystic fibrosis is a life-limiting disease that is caused by defective or deficient
cystic fibrosis transmembrane conductance regulator (CFTR) protein activity. Phe508del is the …
cystic fibrosis transmembrane conductance regulator (CFTR) protein activity. Phe508del is the …
[HTML][HTML] Tezacaftor–ivacaftor in patients with cystic fibrosis homozygous for Phe508del
…, Y Lu, J Lekstrom-Himes, JS Elborn - New england journal …, 2017 - Mass Medical Soc
Background Combination treatment with the cystic fibrosis transmembrane conductance
regulator (CFTR) modulators tezacaftor (VX-661) and ivacaftor (VX-770) was designed to target …
regulator (CFTR) modulators tezacaftor (VX-661) and ivacaftor (VX-770) was designed to target …
Detection of anaerobic bacteria in high numbers in sputum from patients with cystic fibrosis
…, DF Gilpin, A McDowell, JS Elborn - American journal of …, 2008 - atsjournals.org
… Stuart Elborn … Stuart Elborn … McGarvey LP, Dunbar K, Martin SL, Brown V, Macmahon J,
Ennis M, Elborn JS. Cytokine concentrations and neutrophil elastase activity in bronchoalveolar …
Ennis M, Elborn JS. Cytokine concentrations and neutrophil elastase activity in bronchoalveolar …
Cystic fibrosis: current survival and population estimates to the year 2000.
JS Elborn, DJ Shale, JR Britton - Thorax, 1991 - thorax.bmj.com
BACKGROUND: Survival from cystic fibrosis is increasing rapidly. Estimates of the extent of
this improvement should allow health care facilities to be planned to deal with the expanding …
this improvement should allow health care facilities to be planned to deal with the expanding …
[HTML][HTML] British Thoracic Society Guideline for bronchiectasis in adults
CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary ciliary …
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary ciliary …
[HTML][HTML] Recommendations for the classification of diseases as CFTR-related disorders
…, GR Cutting, P Drevínek, P Farrell, JS Elborn… - Journal of Cystic …, 2011 - Elsevier
Several diseases have been clinically or genetically related to cystic fibrosis (CF), but a
consensus definition is lacking. Here, we present a proposal for consensus guidelines on cystic …
consensus definition is lacking. Here, we present a proposal for consensus guidelines on cystic …