Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is
the fourth leading cause of chronic morbidity and mortality in the United States, and is …

Asthma management guidelines provide recommendations for the optimum control of asthma.
This survey assessed the current levels of asthma control as reported by patients, which …

Background Dupilumab is a fully human anti–interleukin-4 receptor α monoclonal antibody
that blocks both interleukin-4 and interleukin-13 signaling. We assessed its efficacy and …

Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV 1 inadequately describes this …

Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and
mortality and represents a substantial economic and social burden throughout the world. It is …

BACKGROUND: In 1995, the Global Initiative for Asthma (GINA) guidelines recommended
goals for the management of asthma, which were updated in 2002. However, there are no …

Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …

Chronic obstructive pulmonary disease (COPD) is defined by fixed airflow limitation
associated with an abnormal pulmonary and systemic inflammatory response of the lungs to …

… Rabe can be contacted at k . f . rabe@ lungenclinic . de or at LungenClinic Grosshansdorf,
Wöhrendamm 80, 22927 Grosshansdorf, … Bhatt and Rabe contributed equally to this article. …