User profiles for S. Janes
Sam JanesUniversity College London Verified email at ucl.ac.uk Cited by 22809 |
Elective surgery after acute diverticulitis
S Janes, A Meagher, FA Frizelle - Journal of British Surgery, 2005 - academic.oup.com
Background Diverticulitis is a common condition. Practice guidelines from many organizations
recommend bowel resection after two attacks. The evidence for such a recommendation is …
recommend bowel resection after two attacks. The evidence for such a recommendation is …
Perspectives on the treatment of malignant pleural mesothelioma
Mesothelioma Most mesotheliomas originate in the pleura and are due to asbestos exposure.
The incidence is decreasing somewhat with asbestos remediation, but mortality remains …
The incidence is decreasing somewhat with asbestos remediation, but mortality remains …
Epidermal stem cells
The clinical implications of understanding epidermal stem cell biology abound. Thousands
of burns victims across the world have benefited from early research into the proliferation of …
of burns victims across the world have benefited from early research into the proliferation of …
[HTML][HTML] Tracking the evolution of non–small-cell lung cancer
…, N Panagiotopoulos, SM Janes… - … England Journal of …, 2017 - Mass Medical Soc
Background Among patients with non–small-cell lung cancer (NSCLC), data on intratumor
heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. …
heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. …
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
…, S Kolvekar, N Panagiotopoulos, SM Janes… - Nature, 2017 - nature.com
The early detection of relapse following primary surgery for non-small-cell lung cancer and
the characterization of emerging subclones, which seed metastatic sites, might offer new …
the characterization of emerging subclones, which seed metastatic sites, might offer new …
[HTML][HTML] Single-cell multi-omics analysis of the immune response in COVID-19
…, E Kilich, A de Wilton, A Saigal, A Saleh, SM Janes… - Nature medicine, 2021 - nature.com
Abstract Analysis of human blood immune cells provides insights into the coordinated
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
…, T Voet, P Van Loo, DM Rassl, RC Rintoul, SM Janes… - Science, 2014 - science.org
… The 95% confidence intervals for Fisher’s exact test are indicated. (D and E) Three mutation
types (C>A; C>G and C>T) at all 16 possible trinucleotide contexts for L002 (D) and L008 (E)…
types (C>A; C>G and C>T) at all 16 possible trinucleotide contexts for L002 (D) and L008 (E)…
[PDF][PDF] Allele-specific HLA loss and immune escape in lung cancer evolution
… We reasoned that, by leveraging the reads that map specifically to an individual’s germline
HLA alleles rather than the human reference genome, it would be possible to accurately deter…
HLA alleles rather than the human reference genome, it would be possible to accurately deter…
A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase
An active site, cofactor-containing peptide has been obtained in high yield from bovine serum
amine oxidase. Sequencing of this pentapeptide indicates: Leu-Asn-X-Asp-Tyr. Analysis of …
amine oxidase. Sequencing of this pentapeptide indicates: Leu-Asn-X-Asp-Tyr. Analysis of …
[HTML][HTML] Local and systemic responses to SARS-CoV-2 infection in children and adults
It is not fully understood why COVID-19 is typically milder in children 1 , 2 – 3 . Here, to examine
the differences between children and adults in their response to SARS-CoV-2 infection, …
the differences between children and adults in their response to SARS-CoV-2 infection, …